Ghali or Al-Ghali may refer to:
- Ghali (rapper), Italian rapper of Tunisian origin
- Boutros Ghali, Egyptian politician
- Fathia Ghali, Egyptian princess
- Mohammad Mahmoud Ghali, Egyptian scholar
- Salah Ali Al-Ghali, Sudanese politician
- Samia Ghali, French politician
- A person belonging to the ghulat (a plural noun derived from Arabic ghali), minority Shia Muslim groups who ascribe divine characteristics to members of Muhammad's family.